Mantova supports scientific research on biomaterials for regenerative medicine
The scientific study that was just published in the journal Materials Science & Engineering C was developed with a polymer produced by Juliano Ernzen, project manager at Mantova, in his Master's dissertation. This polymer, a polyamide 6 (PA6) chemically modified with maleised soybean oil (SOMA), was electrospun and tested as a functional support (or scaffold) for the regeneration of deep skin wounds in rats.
The function of this nanostructure was to provide physical support and biological recognition for the functional tissues forming in the injured skin. The presence of SOMA in the PA6 structure favored cell proliferation and conferred toughness to the polymer, a characteristic that contributes to the manipulation and adequate conformation of the scaffold in the wound bed.
The study was designed by researchers Fernanda Dias and Otávio Bianchi, from the Postgraduate Program in Materials Science and Engineering at the University of Caxias do Sul (PGMAT / UCS) and Natália Nicoletti and Asdrúbal Falavigna, both from the Health Sciences area of UCS. According to the researchers, the biomaterial produced was able to mimic the three-dimensional structure of the extracellular matrix of native tissue and can be used as a carrier for biological molecules and modulating agents in tissue repair processes. The article can be read at https://doi.org/10.1016/j.msec.2019.02.019
Mantova believes that innovations in polymer science and technology should be continuously encouraged in order to boost the generation of new business for the plastics industry.
